15% off your first order when you join our mailing list | Shop Now
Triple-Negative Breast Cancer (TNBC)
$37.00
Introduction
This botanical protocol was developed to support patients with Triple-Negative Breast Cancer (TNBC) using a combination of Traditional Chinese Medicine (TCM) and evidence-informed Western herbal research. Each herb in this 18-herb formula was selected for its relevance to TNBC biology, including its ability to:
Modulate inflammatory and immune pathways
Induce apoptosis and autophagy in breast cancer cell lines
Inhibit metastasis and angiogenesis
Support organ resilience during chemotherapy and radiation
All herbs have demonstrated low toxicity, high therapeutic potential, and compatibility with standard oncologic care in current literature. This formula is offered in both tincture and tea form.
Quantity
TNBC Herbal Protocol – Clinical Overview & Safety
1. Huang Qi (Astragalus membranaceus)
Clinical Highlights: Immune-enhancing, anti-metastatic, marrow-restorative Mechanisms: TGF-β1 and VEGF inhibition, interferon-γ activation, PI3K/Akt modulation Active Compounds: Astragaloside IV, calycosin, polysaccharides Compatibility: Supports chemo/radiation recovery References: Cho WC. Evidence-Based Anticancer Materia Medica; Liu J. Cancer Lett. 2018
2. Bai Hua She She Cao (Hedyotis diffusa)
Clinical Highlights: Apoptosis in TNBC cells, STAT3 inhibition Mechanisms: Upregulates Bax, caspase-3; suppresses PI3K/Akt and ROS pathways Active Compounds: Iridoids, anthraquinones, scutellarein Compatibility: Safe, radiation-protective References: Huang M.Y. J Ethnopharmacol. 2015
3. Ban Zhi Lian (Scutellaria barbata)
Clinical Highlights: Angiogenesis inhibitor, chemo-synergistic Mechanisms: Caspase activation, STAT3/NF-κB suppression Active Compounds: Scutellarein, baicalin, wogonin Compatibility: Compatible with chemo/radiation References: Li-Weber M. Cancer Treat Rev. 2009
4. Shan Dou Gen (Sophora tonkinensis)
Clinical Highlights: TNBC apoptosis, immune enhancement Mechanisms: ROS-mediated DNA damage, JAK/STAT3 inhibition Active Compounds: Matrine, oxymatrine Compatibility: Hepatoprotective with chemo References: Liu J. Biomed Pharmacother. 2017; Zhang Y. J Ethnopharmacol. 2018
5. Yu Xing Cao (Houttuynia cordata)
Clinical Highlights: EMT and metastasis suppression Mechanisms: Inhibits NF-κB, TGF-β, MMP-9 Active Compounds: Quercitrin, houttuynin Compatibility: Supports detox and radiation resilience References: Lu H.M. Front Pharmacol. 2021
6. Zhi Mu (Anemarrhena asphodeloides)
Clinical Highlights: Anti-estrogenic, metabolic regulator Mechanisms: AMPK activation, glucose metabolism inhibition Active Compounds: Timosaponin A-III, mangiferin Compatibility: Balances chemo stress References: Guo X. Phytomedicine. 2014
7. Bai Jiang Cao (Patrinia scabiosaefolia)
Clinical Highlights: Anti-inflammatory, tumor necrosis enhancer Mechanisms: Caspase activation, HIF-1α suppression Active Compounds: Patriscabosides, volatile oils Compatibility: Supports tumor regression with chemo References: Zhang L. J Ethnopharmacol. 2019
8. Chi Shao (Paeonia rubra)
Clinical Highlights: Blood invigoration, antioxidant, apoptosis-inducing Mechanisms: COX-2 inhibition, mitochondrial ROS Active Compounds: Paeoniflorin, gallic acid Compatibility: Reduces toxicity-related stasis References: Wang Y. Phytomedicine. 2018
TNBC Herbal Protocol – Clinical Overview & Safety
9. Dang Shen (Codonopsis pilosula)
Clinical Highlights: Qi restoration, WBC support post-chemo Mechanisms: Cytokine modulation, mucosal repair Active Compounds: Polysaccharides, saponins Compatibility: Widely used with chemotherapy References: Zhang J. J Ethnopharmacol. 2020
10. Gan Cao (Glycyrrhiza uralensis)
Clinical Highlights: Anti-inflammatory, detoxifying, synergist Mechanisms: NF-κB, PI3K/Akt inhibition Active Compounds: Glycyrrhizin, liquiritigenin Compatibility: Caution in hypertension References: Wang Z.Y. Cancer Lett. 2010
11. Ling Zhi (Ganoderma lucidum)
Clinical Highlights: Immune enhancement, NK cell activation Mechanisms: PI3K/Akt suppression, macrophage stimulation Active Compounds: Beta-glucans, ganoderic acids Compatibility: Radioprotective, marrow supportive References: Boh B. Int J Med Mushrooms. 2013
12. Yun Zhi (Turkey Tail – Trametes versicolor)
Clinical Highlights: PSK and PSP immune modulation Mechanisms: IL-2, IFN-γ activation, tumor immune evasion prevention Active Compounds: PSK, PSP Compatibility: Enhances chemo outcomes References: Eliza W. J Clin Oncol. 2005
13. San Leng (Sparganium stoloniferum)
Clinical Highlights: Tumor dispersing, stasis breaking Mechanisms: VEGF/HIF-1α inhibition, apoptosis Active Compounds: Sparganium glycosides Compatibility: Synergistic with chemo References: Liu Y. Phytomedicine. 2019
14. E Zhu (Curcuma zedoaria)
Clinical Highlights: TNBC-specific antimetastatic effects Mechanisms: STAT3, EMT, NF-κB blockade Active Compounds: Curcumol, zedoarondiol Compatibility: Radioprotective, enhances chemo References: Chen H. Phytother Res. 2016
15. Jiao Gu Lan (Gynostemma pentaphyllum)
Clinical Highlights: Adaptogenic, apoptosis-inducing Mechanisms: mTOR, NF-κB inhibition, ROS modulation Active Compounds: Gypenosides, flavonoids Compatibility: Liver/kidney protective References: Zhang H. Oncol Rep. 2014
16. Soursop (Annona muricata)
Clinical Highlights: Cytotoxic to TNBC cells, anti-Warburg Mechanisms: EGFR, NADPH oxidase inhibition, mitochondrial disruption Active Compounds: Acetogenins, annonacin Compatibility: Use in moderation; synergistic References: Torres M.P. BMC Complement Altern Med. 2012
17. Green Tea (Camellia sinensis)
Clinical Highlights: TNBC apoptosis, metabolic inhibition Mechanisms: EGFR, VEGF, AMPK activation Active Compounds: EGCG, catechins Compatibility: Enhances chemo, antioxidant References: Wang W. Cancer Lett. 2014
18. Turmeric (Curcuma longa)
Clinical Highlights: Strong anti-inflammatory, NF-κB and COX-2 inhibitor Mechanisms: Apoptosis via ROS, EGFR and STAT3 suppression Active Compounds: Curcumin, demethoxycurcumin Compatibility: Chemosensitizing, radioprotective References: Aggarwal BB. Biochem Pharmacol. 2007
For further questions, clinical references, or patient coordination, please contact: Mary Spohn, LAc | 623-388-2431 | marytealady@gmail.com | www.lumatea.com
