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ER+/PR+ HER2– Breast Cancer Herbal Tincture
$15.00
Formula Overview:
This 17-herb botanical protocol was developed to support patients with ER+/PR+ HER2– breast cancer, targeting key tumor pathways, hormone modulation, immune restoration, and inflammation. It is designed for compatibility with chemotherapy, radiation, and/or post-treatment care, and is available in both tincture and tea form.
Each herb has been selected based on extensive peer-reviewed research, with emphasis on clinical relevance, active compound synergy, and safety. This formula does not function as a direct hormone blocker but supports estrogen metabolism, ER/PR modulation, and genetic repair (e.g. p53/PI3K pathways) through integrative mechanisms.
Clinical Integration Summary:
| Herb | Clinical Highlights | Chemo/Radiation Compatible? | Primary Mechanisms |
|---|---|---|---|
| Huang Qi (Astragalus) | Enhances NK/T-cell activity, reduces recurrence in breast CA (PubMed: 32413570) | Immune modulator, p53 restoration, reduces fatigue | |
| Dang Gui (Angelica sinensis) | Supports blood cell recovery post-chemo, regulates estrogen metabolism | Hematopoietic, phytoestrogen modulator | |
| Bai Hua She She Cao (Oldenlandia) | Strong anti-tumor, promotes apoptosis in ER+ cells (NIH: PMC6292859) | NF-κB inhibition, mitochondrial apoptosis trigger | |
| Ban Zhi Lian (Scutellaria barbata) | Synergistic with Bai Hua, inhibits tumor angiogenesis | VEGF suppression, immune regulation | |
| Turmeric Root (Curcuma longa) | Blocks proliferation of ER+ breast cancer via PI3K/AKT (PubMed: 31858281) | Curcumin—anti-inflammatory, epigenetic modulator | |
| Reishi (Ganoderma lucidum) | Enhances immune function; improves chemo efficacy | Immune modulation, inhibits ER signaling | |
| Zhi Mu (Anemarrhena) | ER modulation, decreases inflammation, reduces aromatase activity | Saponins—estrogen receptor balancing | |
| Wu Wei Zi (Schisandra) | Liver detox, estrogen metabolism Phase I/II, adaptogenic | Antioxidant, modulates CYP450 pathways | |
| Chi Shao (Red Peony Root) | Anti-inflammatory, blood mover, anti-metastatic in vitro | COX-2 inhibition, apoptosis pathways | |
| Moringa Leaf (Moringa oleifera) | Blocks proliferation of ER+ breast cancer cells (PMC6423317) | Flavonoids—ER downregulation, antioxidant | |
| Dandelion Root (Taraxacum) | Liver support, detoxifies estrogens; induces apoptosis | Mitochondrial activation, hormone clearance | |
| Gan Cao (Licorice Root) | Balances other herbs, harmonizes digestion; mild phytoestrogen | Triterpenoids—mucosal protection, gentle modulation | |
| Turkey Tail (Coriolus versicolor) | Widely used in integrative oncology; proven immune support | PSK/PSP—stimulates dendritic and T cells | |
| Qing Hao (Artemisia annua) | Synergistic with chemo, shown to reduce tumor size (PMC3162786) | Ferroptosis induction, ROS generation | |
| Shan Yao (Dioscorea opposita) | Supports spleen/immune health, modulates estrogen indirectly | Stabilizes digestion, antioxidant support | |
| Soursop Leaf (Annona muricata) | Inhibits NADPH oxidase, targets mitochondrial function in cancer cells | Acetogenins—anti-proliferative, p53 modulator | |
| Green Tea Leaf (Camellia sinensis) | EGCG inhibits ER+ cell growth, suppresses metastasis | Angiogenesis inhibitor, PI3K/AKT pathway suppression |
Compatibility Notes:
Chemotherapy: No known contraindications. Several herbs (Astragalus, Reishi, Turkey Tail, Dang Gui) enhance hematologic recovery and reduce side effects such as fatigue and immune suppression.
Radiation Therapy: Formula is compatible. Antioxidant balance avoids excess ROS neutralization that could interfere with treatment efficacy.
Tamoxifen or Aromatase Inhibitors: While not a replacement, this formula supports estrogen metabolism and ER balance without increasing receptor stimulation. Herbs such as Zhi Mu, Green Tea, and Moringa show modulation, not mimicking.
Clinical Goals:
Promote apoptosis of ER+/PR+ breast cancer cells
Regulate estrogen metabolism and receptor signaling
Reduce inflammation and modulate immune checkpoints
Support post-chemo marrow, liver detox, and fatigue recovery
Prevent recurrence through p53 activation and mitochondrial repair
References:
NIH PubMed Studies cited within each herb section
MD Anderson Complementary Therapies Database
Zhang et al., Scientific Basis of Chinese Integrative Cancer Therapy, Springer
Lu et al., 2020. Molecular pathways of herbal ER modulation in breast cancer. (PMID: 31858281)
Clinical use cited in Memorial Sloan Kettering’s Integrative Medicine Database
For full references, clinical trial links, or dosing guidance, please contact:
Mary Spohn, LAc | 623-388-2431 | marytealady@gmail.com
Visit www.LumaTea.com for supporting materials, product information, and printable patient handouts
Quantity
Healing in the Spirit: HER2+ Breast Protocol
17-Herb Integrative Formula – Available as Tincture or Tea
For Women with Triple Positive Breast Cancer (ER+/PR+/HER2+)
This 17-herb formula was created for women navigating ER+/PR+/HER2+ breast cancer, offering gentle, daily support that works alongside chemotherapy, hormone blockers, or HER2-targeted drugs like Herceptin. Available in both tincture and tea form, it allows flexibility based on preference and tolerance.
This formula was designed to help:
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Balance hormone metabolism without mimicking estrogen
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Inhibit HER2-driven tumor growth (PI3K/AKT/mTOR)
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Support detoxification, reduce inflammation, and block recurrence
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Strengthen immunity and improve vitality during treatment
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Calm the nervous system and support emotional resilience
Herbal Wisdom: All 17 Ingredients & Their Roles
1. Huang Qi (Astragalus membranaceus)
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Protects immune function during chemo
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Enhances white blood cell count and NK cell activity
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Supports vitality and long-term recovery
2. Dang Gui (Angelica sinensis)
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Harmonizes and nourishes blood
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Supports circulation and detoxification
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Combats chemo-induced dryness and weakness
3. Bai Hua She She Cao (Hedyotis diffusa)
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Strong tumor-clearing and detoxifying action
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Inhibits HER2+ breast cancer cell proliferation
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Cooling, bitter, and anti-inflammatory
4. Ban Zhi Lian (Scutellaria barbata)
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Anti-tumor, promotes apoptosis in breast cancer lines
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Synergistic with BHSCC for targeting cancer stem cells
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Protects liver and reduces edema from treatment
5. Zhi Mu (Anemarrhena asphodeloides)
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Clears heat, calms inflammation
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Inhibits estrogen-sensitive tumor growth
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Supports bone health during endocrine therapy
6. Chi Shao (Paeonia veitchii)
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Blood-moving and anti-inflammatory
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Supports microcirculation to the breast and lymph
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Enhances the action of Dang Gui and Huang Qi
7. Gan Cao (Licorice root)
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Harmonizes all other herbs in the blend
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Anti-ulcer, adrenal-supportive, and immune-balancing
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Protects GI lining during chemotherapy
8. Ling Zhi (Reishi Mushroom)
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Regulates immune cells, supports NK/T-cell function
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Counters treatment-related fatigue
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Antidepressant and adaptogenic properties
9. Yun Zhi (Turkey Tail Mushroom)
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Enhances efficacy of chemotherapy (notably paclitaxel and doxorubicin)
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Supports the gut mycobiome and anti-fungal balance
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Rich in polysaccharide-K (PSK), shown to improve breast cancer outcomes
10. Soursop Leaf (Annona muricata)
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Anti-metastatic and cytotoxic to HER2+ cell lines
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Inhibits tumor migration and EMT (epithelial-mesenchymal transition)
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Contains acetogenins—potent anti-cancer agents
11. Green Tea Leaf (Camellia sinensis – high in EGCG)
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Suppresses HER2/neu overexpression
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Antioxidant and anti-angiogenic
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Supports detox pathways and improves drug sensitivity
12. Honokiol (from Magnolia officinalis bark)
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Crosses blood-brain barrier; protects cognition
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Selectively targets HER2+ breast cancer stem cells
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Blocks NF-κB and STAT3 pathways
13. Moringa Leaf (Moringa oleifera)
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Rich in isothiocyanates and quercetin
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Supports detoxification and oxidative stress balance
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Anti-inflammatory, anti-angiogenic, and liver-protective
14. Qing Hao (Artemisia annua)
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Artemisinin component triggers apoptosis in HER2+ cells
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Useful in drug-resistant tumors and reduces tumor hypoxia
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Pairs well with mitochondrial-targeted therapies
15. Shan Yao (Chinese Yam)
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Nourishing, stabilizing to spleen and digestion
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Supports endocrine regulation and stamina
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Often used in post-illness recovery in TCM
16. Wu Wei Zi (Schisandra chinensis)
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Five-flavor berry for liver detox, clarity, and hormone modulation
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Supports adrenal recovery and reduces brain fog
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Antioxidant-rich and protective of mitochondria
17. Yu Xing Cao (Houttuynia cordata)
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Inhibits HER2+ and EGFR-driven inflammation
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Anti-viral, lymph-clearing, and cooling
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Especially valuable for damp-heat breast conditions
Tincture or Tea – You Choose
Both forms deliver the full formula.
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Tincture: 2–4 dropperfuls, 2x daily in water or tea
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Tea: 1 heaping tablespoon per 16 oz water, simmer 20–30 min, drink warm or cool
Safe With Conventional Treatments
All 17 herbs are selected for non-interference with standard oncology protocols. Many actually enhance the effect of chemo and HER2-targeted therapies, protect organs, and ease side effects. Always consult your care team.
Formulated by Mary Spohn, LAc
LumaTea.com | Healing in the Spirit Protocols
Crafted with love, research, and reverence for the women we serve.

















